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KMID : 1200020120360060433
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Diabetes & Metabolism Journal
2012 Volume.36 No. 6 p.433 ~ p.442
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Chronic Kidney Disease and Associated Cardiovascular Risk Factors in Chinese with Type 2 Diabetes
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Lou Qing-Lin
Ouyang Xiao-Jun
Gu Liu-Bao
Mo Yong-Zhen
Ma Ronald
Nan Jennifer
Kong Alice
So Wing-Yee
Ko Gary
Chan Juliana
Chow Chun-Chung
Bian Rong-Wen
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Abstract
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Background: To determine the frequency of chronic kidney disease (CKD) and its associated risk factors in Chinese type 2 diabetic patients, we conducted a cross-sectional study in Nanjing, China, in the period between January 2008 and December 2009.
Methods: Patients with type 2 diabetes under the care by Jiangsu Province Official Hospital, Nanjing, China were invited for assessment. CKD was defined as the presence of albuminuria or estimated glomerular filtration rate <60 mL/min/1.73 m2. Albuminuria was defined as urinary albumin-to-creatinine ratio ≥30 mg/g.
Results: We recruited 1,521 urban Chinese patients with type 2 diabetes (mean age, 63.9±12.0 years). The frequency of CKD and albuminuria was 31.0% and 28.9%, respectively. After adjusted by age and sex, hypertension, anemia and duration of diabetes were significantly associated with CKD with odds ratio (95% confidence interval) being 1.93 (1.28 to 2.93), 1.70 (1.09 to 2.64), and 1.03 (1.00 to 1.06), respectively.
Conclusion: In conclusion, CKD was common in the urban Nanjing Chinese with type 2 diabetes. Strategies to prevent or delay progression of kidney disease in diabetes should be carried out at the early disease course of type 2 diabetes.
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KEYWORD
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Albuminuria, Chronic kidney disease, Diabetes mellitus, type 2, Risk factors
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